___
___ lo
(1) lo as the direct object form of "el"
lo vemos We see him
(2) lo as the "neuter" form of the personal pronoun.
It usually refers to something previously mentioned and is most commonly translated by "it".
In English it may be redundant and it often disappears from the translation.
No quise hacerlo I did not want to do it
Lo hice por ayudarte I did it to help you
Repitelo otra vez Repeat [it] once more
¿Cuàntas veces tengo que repetirlo? How many times do I have to repeat [it]?
Si llegas a saberlo, !cuentamelo! If you manage to know, tell me!
Deberías decirselo You should tell her | him
(3) lo que What =Fr. ce que
Lo que usted necesita es descansar mucho What you need is to rest
¿Qué vas a comprar? Comprare lo que necesito What are you going to buy? I'll buy what I need
(4) lo más ...
Lo más pronto possible As soon as possible